Peyton Manning has played the Cowboys four times. He is 2-2, having lost the last two. Manning has completed 67.3 percent of his passes for 1,184 yards with seven touchdowns and seven interceptions and a passer rating of 85.5.
In a 2010 game, Dallas upset Manning's Colts 38-35 as Sean Lee had two of the team's four interceptions against Manning. Lee returned his first interception 31 yards for a touchdown, and his second pick led to a game-winning field goal in overtime.
"I still have that [game] ball," Lee said Wednesday. "That’s one of my [top] plays, and that was a great win for us. Anytime you go into Indianapolis against that team, it was a tough game, and we won. I thought it was a great win for us, but this is a new year and a different time and different team. This is going to be an extreme challenge."
Lee is the only active player with picks of both Manning and Tom Brady, two of the greatest quarterbacks in NFL history. Lee, though, wasn't interested in talking about the past. His future is this week in a second career appearance against Manning.
"Some of those picks were the guys getting pressure, and there were some situational things that helped me," Lee said. "I’m looking straight forward to this game, and I’m trying to concentrate on this year and improving from the Chargers game with the mistakes we made and try to get a win against this great team."
Lee had his second career interception return for a touchdown last Sunday, with a 52-yarder against Chargers quarterback Philip Rivers. But it came in a losing cause.
Lee has allowed four touchdowns this season, second in the NFL, according to STATS. He has given up 12 catches for 153 yards. He allowed the game-clinching touchdown Sunday when Chargers tight end Antonio Gates caught a 56-yard score in the fourth quarter.
"There were some mistakes that were made that we’re going to have to improve on," Lee said. "Technique-wise, we can play wiser against routes. We can’t give up big plays. That’s what we gave them in the Chargers game, and that’s why we lost.
"If we give up big plays, we’re going to be in trouble against this offense."
-- Charean Williams